Gleazy

• Approved Indications
• Ophthalmic Use (Artificial Tears / Lubricants)
• Relief of dry eye symptoms such as irritation, burning, and foreign body sensation
• Management of mild to moderate keratoconjunctivitis sicca
• Ocular Surface Protection
• Temporary relief from exposure-related dryness (air conditioning, prolonged screen time, contact lens use)
• Off-label / Clinically Accepted Uses
• Lubrication for post-surgical ocular surface recovery
• Adjunct therapy in certain inflammatory or degenerative ocular surface disorders

• Adults and Children
• Instill 1–2 drops in the affected eye(s) 3–6 times daily, or as needed for symptom relief
• Elderly
• Same dosing; monitor for adherence and ability to self-administer
• Special Populations
• No dosage adjustment required for mild renal or hepatic impairment
• Administration Notes
• Wash hands before use
• Avoid touching the tip of the dropper to the eye or any surface to prevent contamination
• Remove contact lenses prior to instillation; may reinsert after 15 minutes

Hydroxyethyl cellulose is a hydrophilic polymer that increases tear viscosity, enhancing ocular surface lubrication and retention time of tears. Glycerin acts as a humectant, drawing water into the corneal epithelium and maintaining moisture. Together, they form a protective film on the eye surface, reducing friction, minimizing irritation, and promoting epithelial healing.

• Absorption: Minimal systemic absorption via the ocular route
• Distribution: Localized primarily to the tear film and ocular surface
• Metabolism: Not systemically metabolized
• Excretion: Eliminated via natural tear drainage
• Onset: Immediate symptomatic relief upon instillation
• Duration: Effects last several hours depending on tear film stability and severity of dryness

• Pregnancy: Considered Category C (no controlled human studies); topical ocular use has negligible systemic absorption, making risk minimal
• Breastfeeding: Safe for use during lactation; minimal systemic absorption implies negligible exposure to the infant
• Caution: As with all ocular products, consult a healthcare provider if used frequently

• Primary Class: Ophthalmic lubricant / Artificial tear
• Subclass: Viscosity-enhancing polymer with humectant

• Known hypersensitivity to hydroxyethyl cellulose, glycerin, or any excipients
• Eye infection or corneal ulcer unless under physician supervision

• Avoid contamination of the dropper tip to prevent secondary eye infections
• Do not use if solution changes color or becomes cloudy
• Discontinue use if eye pain, redness, or visual disturbance occurs and seek medical advice
• High-risk patients: immunocompromised individuals, post-surgical eyes

• Common: Temporary mild stinging or burning upon instillation
• Ocular: Blurred vision immediately after administration (resolves within minutes)
• Rare: Allergic conjunctivitis or eyelid edema
• Timing: Usually occurs immediately and resolves quickly; no dose-dependence noted

• Minimal systemic absorption means negligible drug-drug interactions
• Can be used concomitantly with other topical ophthalmic medications; administer at least 5–10 minutes apart to avoid dilution
• No significant interactions with food or alcohol

• Guideline Recommendations: Artificial tears with hydroxyethyl cellulose and glycerin are recommended as first-line management for dry eye syndrome in TFOS DEWS II guidelines
• Emphasis on preservative-free formulations for frequent use to minimize ocular surface toxicity
• No changes in approved indications or dosing in recent years

• Store at 20°C to 25°C (room temperature)
• Protect from light, moisture, and freezing
• Keep the bottle tightly closed when not in use
• Avoid contamination of the dropper tip
• Discard after 30 days of opening to prevent microbial growth