Tea Tree Oil + Geothermal Water + Vitamin E

Approved and Clinically Accepted Uses:

• Acne Vulgaris (Mild to Moderate): Reduces bacterial load (especially Cutibacterium acnes), inflammation, and sebum production.
• Seborrheic Dermatitis & Scalp Conditions: Soothes itchiness, reduces fungal overgrowth, and supports scalp hydration.
• Atopic Dermatitis / Eczema (Mild Cases): Provides anti-inflammatory relief and supports skin barrier repair.
• Minor Skin Infections & Cuts: Acts as an antiseptic to prevent infection in superficial wounds.
• Sunburn and Thermal Burns (1st Degree): Geothermal water and Vitamin E provide cooling, antioxidant, and regenerative support.
• Post-Procedure Dermatologic Care: Promotes healing and soothes skin after laser, peel, or microdermabrasion.
• Skin Redness & Sensitivity: Geothermal water calms erythema in rosacea-prone or reactive skin.
• Hyperpigmentation (Adjunctive Use): Antioxidant support from Vitamin E helps minimize post-inflammatory pigmentation.

Adults and Adolescents (≥12 years):

• Apply a thin layer to affected area 1–3 times daily depending on product strength and skin sensitivity.
• For acne: Spot-apply or spread over affected zones after cleansing.
• For dermatitis or burns: Apply gently to the irritated or inflamed area twice daily.

Children (<12 years):

• Use under supervision; apply once daily to small areas with minimal concentration, if deemed appropriate by a pediatrician.

Elderly:

• No specific adjustments; monitor for increased skin sensitivity or dryness.

Renal/Hepatic Impairment:

• No dose adjustment needed; not systemically absorbed in clinically relevant quantities.

Route of Administration:

• Topical (skin application only); avoid contact with mucous membranes and eyes.

Duration:

• Continue until resolution of symptoms or as directed by a physician; typically 2–8 weeks for acne or dermatitis.

Tea Tree Oil (Melaleuca alternifolia) contains terpinen-4-ol, its main active component, which exhibits broad-spectrum antimicrobial, antifungal, and anti-inflammatory activity by disrupting microbial membranes and inhibiting pro-inflammatory cytokines. Geothermal water is rich in minerals like selenium, zinc, and silica, which soothe irritation, reinforce skin defenses, and reduce oxidative stress. Vitamin E (tocopherol) acts as a potent lipid-soluble antioxidant, protecting cell membranes from free radicals, accelerating wound healing, and maintaining skin hydration. The combination offers a synergistic effect that supports antimicrobial action, skin repair, and anti-inflammatory relief.

• Absorption: Minimal systemic absorption through intact skin; enhanced penetration in broken or inflamed skin.
• Distribution: Localized to the site of application; does not enter systemic circulation in clinically significant amounts.
• Metabolism: If absorbed, metabolized hepatically (Vitamin E and terpinen-4-ol).
• Excretion: Trace amounts may be excreted via urine; clinically insignificant.

Onset of Action:

• Anti-inflammatory relief typically seen within 24–48 hours.
• Antimicrobial effects begin within hours but become clinically evident after several days of consistent use.

Half-life: Not systemically relevant.

• Pregnancy:
  • No official FDA pregnancy category.
  • Generally considered safe in topical formulations during pregnancy when used in small amounts and not applied over large surface areas.
  • Avoid use in broken skin or prolonged exposure due to lack of systemic safety data.
• Lactation:
  • Considered safe when used on non-breast skin areas.
  • Avoid application on or near the nipple to prevent infant ingestion.
  • Minimal risk of systemic absorption or excretion into breast milk.

• Primary Class: Topical Antiseptic + Skin Protectant
• Subclass: Natural Antimicrobial + Mineral Therapeutic + Antioxidant Complex

• Known hypersensitivity to Tea Tree Oil, Vitamin E, geothermal minerals, or formulation excipients
• Broken or extensively damaged skin (if alcohol-based or high-potency formulation is used)
• Infants <6 months (unless physician-supervised)
• Active allergic dermatitis due to plant-derived ingredients

• Allergic Reactions: May cause contact dermatitis in sensitive individuals (patch test recommended before first use).
• Eye and Mucosal Exposure: Avoid contact; can cause irritation or burning.
• Photosensitivity Risk: Rarely associated with photosensitive reactions; sunscreen use advised.
• Pediatric Use: Avoid in very young children unless recommended.
• Extended Use: Do not use for prolonged periods without medical supervision, especially on large areas.
• Product Type Matters: Alcohol-based or highly concentrated essential oil forms can increase risk of irritation.

Common (Localized Skin):

• Mild burning or stinging
• Dryness or flaking
• Redness or irritation (especially in sensitive skin)
• Itchiness

Less Common / Serious:

• Allergic contact dermatitis
• Photosensitivity reactions
• Blistering or eczema flare (if misused or overapplied)

Rare:

• Systemic allergic reactions (extremely rare and typically due to hypersensitivity)

• Topical Interactions:
  • May increase skin dryness or irritation when combined with retinoids, benzoyl peroxide, or salicylic acid.
  • Use caution with concurrent corticosteroids – may reduce antiseptic efficacy.
• Systemic Drug Interactions:
  • None clinically significant due to minimal absorption.
• Enzyme Interaction:
  • Tea Tree Oil may inhibit CYP2C9 and CYP3A4 in vitro but irrelevant with topical use.

• Expanded Use in Sensitive Skin Regimens: Recent dermatologic consensus supports the use of geothermal water and Vitamin E in post-procedure care and skin barrier therapy.
• Allergen Surveillance: Ongoing monitoring by cosmetic safety boards has led to enhanced labeling recommendations for Tea Tree Oil concentration limits in over-the-counter skincare.
• Trend Toward Synergistic Formulations: Multi-ingredient approaches (e.g., combining antimicrobial, anti-inflammatory, and barrier-restoring agents) are now preferred in acne and dermatitis care.

• Temperature: Store at 15°C to 25°C (59°F to 77°F)
• Protection: Keep away from direct sunlight and excessive moisture
• Container: Use original sealed container; close tightly after each use
• Handling: Shake well if labeled; avoid contamination of applicator tip
• Shelf Life: Typically 12–36 months depending on packaging and preservatives used
• Special Instructions: Do not freeze. If oil separates, mix gently before use.