ScarFix

 20 mg Gel
Incepta Pharmaceuticals Ltd.
20 mg Tube: ৳250.00
Indications

Allantoin + Allium Cepa is a topical combination used for the treatment and prevention of various types of scars. It is indicated for:

  • Hypertrophic scars and keloids (thick, raised scars caused by excessive collagen formation)
  • Post-surgical scars (e.g., after cesarean section, orthopedic surgery, plastic surgery)
  • Post-burn scars
  • Acne scars
  • Stretch marks (striae distensae) from pregnancy, weight gain, or growth spurts
  • Skin damage due to trauma or injury

This combination helps reduce scar height, redness, stiffness, and discoloration, and improves skin texture and elasticity over time.

রেজিস্টার্ড চিকিৎসকের নির্দেশনা অনুযায়ী ঔষধ সেবন করুন।

Dosage & Administration

Allantoin + Allium Cepa is applied topically to intact skin. Use should begin after complete wound healing (once the skin is closed and dry).

  • Apply a thin layer over the affected area and massage gently until fully absorbed.
  • Use 2 to 3 times daily, consistently, for at least 8 weeks. Older or more severe scars may require up to 6 months of treatment.
  • Safe for use in adults, elderly, and children above 2 years, under supervision.

Do not apply on open wounds, broken skin, mucous membranes, or infected areas. Avoid contact with eyes and mouth.

রেজিস্টার্ড চিকিৎসকের নির্দেশনা অনুযায়ী ঔষধ সেবন করুন।

Mechanism of Action (MOA)

This combination works by combining the effects of two different active components:

  • Allantoin is a keratolytic and skin protectant. It promotes hydration, soothing, and cellular regeneration. It increases water content in the extracellular matrix and softens keratin, helping smooth and repair scar tissue.
  • Allium Cepa extract (derived from onion) contains quercetin, sulfur compounds, and flavonoids with anti-inflammatory, antibacterial, and anti-proliferative properties. It reduces fibroblast proliferation and collagen synthesis—key mechanisms involved in hypertrophic scar and keloid formation.

Together, they reduce scar thickness, redness, and discomfort, improve cosmetic appearance, and support the natural healing process.

Pharmacokinetics

Being a topical agent, systemic absorption is minimal.

  • Absorption: Primarily local to the area of application
  • Distribution: Localized in epidermal and dermal layers
  • Metabolism: Negligible systemic metabolism
  • Excretion: Eliminated through natural skin turnover; not excreted via kidneys or liver in measurable amounts

Systemic exposure is extremely low, making it safe for prolonged use in most populations.

Pregnancy Category & Lactation
  • Pregnancy: Topical use is considered low-risk, as systemic absorption is minimal. However, safety has not been conclusively established in pregnant women. Use only if clearly needed and under medical supervision.
  • Lactation: Safe when applied away from the breast area. Avoid application on or near nipples to prevent accidental ingestion by nursing infants.
Therapeutic Class
  • Topical Scar Treatment Agent
  • Combination: Botanical Extract + Keratolytic Agent
Contraindications

Do not use Allantoin + Allium Cepa in the following cases:

  • Known hypersensitivity to Allantoin, Allium Cepa, or any ingredients in the formulation
  • Application on open wounds, bleeding areas, or infected skin
  • Use on mucosal surfaces such as eyes, mouth, genitals, or inside the nose
Warnings & Precautions
  • For external use only
  • Discontinue use if skin irritation, redness, itching, or rash develops
  • Do not use on deep or infected wounds without medical advice
  • Avoid exposure to sunlight on the treated area unless using sun protection, as scar tissue is more sensitive to UV damage
  • Keep away from children's reach
  • Do not use with strong exfoliants or other irritating topical agents unless prescribed
Side Effects

Allantoin + Allium Cepa is generally well tolerated. However, some users may experience:

Common (mild and temporary):

  • Redness
  • Dryness
  • Itching or stinging
  • Mild burning sensation

Rare (serious):

  • Allergic contact dermatitis
  • Skin rash or swelling
  • Blistering (in case of hypersensitivity)

In case of any serious reaction, discontinue the product and consult a healthcare provider.

Drug Interactions
  • Topical Use: No significant systemic drug interactions are known.
  • Avoid simultaneous application with:
    • Topical retinoids
    • Salicylic acid
    • Benzoyl peroxide
    • Other potentially irritating skin agents

There are no known food or alcohol interactions due to the topical route of administration.

Recent Updates or Guidelines
  • Dermatology guidelines often recommend onion extract-based topical therapies like Allium Cepa for scar prevention, especially in the early stages after healing.
  • It is widely accepted as a non-invasive, first-line treatment for scar management.
  • Several studies have shown that earlier and consistent application leads to better cosmetic outcomes, especially for post-surgical scars and burns.
Storage Conditions
  • Store below 25°C (room temperature)
  • Keep away from direct sunlight, heat, and moisture
  • Do not refrigerate or freeze
  • Keep the container tightly closed after each use
  • Use within the expiry date mentioned on the packaging
Available Brand Names

No other brands available