AREDS

• Slows progression of intermediate and advanced age-related macular degeneration (AMD).
• Helps reduce symptoms of dry eye syndrome by decreasing ocular inflammation.
• Protects retinal and macular cells from oxidative damage and harmful blue light.
• Supports prevention of cataracts by providing antioxidant protection.
• May serve as adjunctive support in diabetic retinopathy and glaucoma.
• Promotes general eye health, especially for individuals exposed to digital screens or environmental stressors.

Each softgel capsule contains-

1.      Vitamin C (Ascorbic Acid): 500 mg

2.      Vitamin E (as Natural d-alpha-tocopherol): 400 IU

3.      Zinc (as Zinc Oxide): 80 mg (some modern formulas use 25–40 mg for better tolerability)

4.      Copper (as Cupric Oxide): 2 mg

5.      Lutein: 10 mg

6.      Zeaxanthin: 2 mg

7.      Omega-3 Fatty Acids (EPA + DHA): Typically 350–1000 mg combined (amount varies by manufacturer)

• Take one softgel capsule daily with a meal to improve absorption of fat-soluble nutrients.
• Suitable for adults and elderly; not recommended for children.
• Use with caution in patients with kidney or liver impairment; consult a healthcare professional.
• Pregnant or breastfeeding women should use only under medical supervision.

Combines antioxidants (vitamins C and E, lutein, zeaxanthin), essential minerals (zinc, copper), and omega-3 fatty acids (EPA and DHA). Lutein and zeaxanthin accumulate in the macula, filtering blue light and neutralizing free radicals. Vitamins C and E protect retinal cells from oxidative damage. Zinc supports retinal enzyme function and immune health, while copper prevents zinc-induced deficiency. Omega-3 fatty acids stabilize retinal membranes and reduce inflammation.

• Fat-soluble nutrients are absorbed in the presence of dietary fats.
• Lutein and zeaxanthin concentrate in the macula; omega-3 fatty acids incorporate into retinal membranes.
• Vitamins and minerals are metabolized primarily in the liver and excreted via urine and bile.

• Generally safe at recommended doses; however, consult a healthcare provider before use.
• Vitamin E should be used cautiously during pregnancy due to bleeding risk.
• Nutrients are naturally present in breast milk and may support infant eye development.

Ophthalmic nutritional supplement containing antioxidants, minerals, and omega-3 fatty acids, based on AREDS2 formulation.

• Allergy to any of the ingredients.
• Active bleeding disorders or concurrent use of high-dose anticoagulants.
• Wilson’s disease or other copper metabolism disorders.
• Severe renal impairment.

• Increased bleeding risk with concurrent anticoagulant or antiplatelet therapy (due to vitamin E).
• Long-term zinc use requires monitoring to prevent copper deficiency.
• Use cautiously in patients with liver disease.
• Discontinue use and seek medical attention if allergic reactions or unexplained symptoms occur.

Common: mild nausea, stomach upset, metallic taste.
Rare: allergic skin reactions, bleeding tendencies, or anemia from copper deficiency.

• Vitamin E may increase bleeding risk when combined with anticoagulants like warfarin.
• Zinc can impair absorption of tetracycline and fluoroquinolone antibiotics; separate doses by at least 2 hours.
• May interfere with iron supplement absorption.
• Absorption of fat-soluble vitamins may be reduced by bile acid sequestrants or orlistat.

• AREDS2 trial replaced beta-carotene with lutein and zeaxanthin due to lung cancer risk in smokers.
• Zinc dosage in newer supplements reduced to improve tolerance without losing efficacy.
• Omega-3 fatty acids added in some products for additional anti-inflammatory and ocular benefits.
• Professional ophthalmology associations recommend AREDS2 supplements for patients with intermediate AMD.

• Store at room temperature (20–25°C).
• Protect from moisture, heat, and direct sunlight.
• Do not freeze.
• Keep container tightly closed.