Zinc Oxide + Castor Oil

Approved and Widely Recognized Uses:

• Diaper rash (diaper dermatitis): First-line topical treatment to prevent and treat irritant contact dermatitis in infants.
• Minor skin irritations: Such as chafing, abrasions, eczema, insect bites, and burns.
• Pressure ulcers (stage I and II): As a protective barrier to reduce further irritation.
• Contact dermatitis: To protect skin from further exposure and aid healing.
• Post-radiation skin care: In patients undergoing radiotherapy to soothe and protect affected skin.

Clinically Accepted Off-label/Nutraceutical Uses:

• Nipple soreness in lactating mothers (short-term use with proper cleaning before breastfeeding).
• Perianal irritation and hemorrhoid-associated discomfort: As a soothing protective agent.
• Tattoo healing support: Used topically in some skin recovery protocols.

রেজিস্টার্ড চিকিৎসকের নির্দেশনা অনুযায়ী ঔষধ সেবন করুন।

General Administration:

• Frequency: Apply 2 to 4 times daily or after each diaper change.
• Clean and dry the affected area before application.

Pediatric (Infants – Diaper Rash):

• Apply a thick layer at each diaper change, especially before bedtime or prolonged exposure to moisture.

Adults:

• Use on minor skin irritations as needed. Reapply every 4–6 hours if required, depending on skin condition and exposure.

Elderly:

• No specific dosage adjustments. Ensure skin is clean and intact before application.

Renal/Hepatic Impairment:

• No known systemic absorption concerns requiring adjustment.

Special Instructions:

• For external use only.
• Avoid contact with eyes or mucous membranes.
• Do not apply to deep puncture wounds or serious burns unless directed.

রেজিস্টার্ড চিকিৎসকের নির্দেশনা অনুযায়ী ঔষধ সেবন করুন।

Zinc oxide acts primarily as a physical barrier and skin protectant by forming an occlusive layer on the skin, thereby preventing further irritation and moisture loss. It has mild astringent and antiseptic properties that support skin healing and reduce inflammation. Castor oil serves as an emollient and humectant, promoting moisture retention in the skin and aiding in the dispersion and penetration of zinc oxide. The combination enhances the protective, soothing, and healing effects on irritated or inflamed skin, especially in moisture-associated skin conditions such as diaper dermatitis.

Pregnancy:

• Considered safe for topical use during pregnancy.
• Zinc oxide and castor oil have a long history of use in over-the-counter skin preparations.
• No known fetal risks with external application.

Lactation:

• Generally safe during breastfeeding.
• If used on the nipple area, ensure complete removal before nursing.
• No reported adverse effects in breastfed infants from maternal use.

• Primary Class: Skin Protectant / Topical Barrier Agent
• Subclass: Combination of inorganic protectant (zinc oxide) and emollient (castor oil)

• Hypersensitivity to zinc oxide, castor oil, or any formulation excipients.
• Severe or deep skin wounds unless advised by a physician.
• Infected or exudative dermatoses (unless under medical supervision).

• For external use only – do not ingest.
• Discontinue use if irritation, rash, or allergic reaction develops.
• Avoid use on infected, bleeding, or oozing wounds without medical advice.
• Occlusive application may cause maceration or secondary infection if not monitored.
• Keep out of reach of children.

Common (usually mild and localized):

• Mild skin irritation or itching
• Transient burning or stinging sensation
• White residue on skin

Rare/Serious Reactions:

• Allergic contact dermatitis
• Secondary infection due to occlusion if applied to unclean or open wounds
• Folliculitis (with overuse or poor hygiene)

Side effects are rare and usually reversible upon discontinuation.

• AAP and CDC continue to recommend zinc oxide-based barrier creams as first-line agents in managing diaper rash.
• No regulatory changes or safety warnings issued regarding the zinc oxide + castor oil combination.
• Products containing these ingredients remain Category I (generally recognized as safe and effective) by the FDA OTC monograph system.

• Temperature: Store at 15°C–30°C (59°F–86°F)
• Humidity: Keep tightly closed in a dry place
• Light Protection: Avoid prolonged exposure to direct sunlight
• Handling: Keep container sealed; do not refrigerate
• Reconstitution: Not required; ready-to-use topical formulation