Urea, SyriCalm, Shea butter, Oil complex omega plus, hydrolyzed silk & glycine soja oil

• Management of dry, rough, scaly, and sensitive skin conditions, including:
• Xerosis (dry skin)
• Atopic dermatitis and eczema (as supportive skin barrier therapy)
• Psoriasis and other hyperkeratotic dermatoses
• Mild to moderate skin irritation and inflammation
• Restoration of skin hydration and barrier function
• Relief of itching and discomfort associated with dry or irritated skin
• Adjunctive use in cosmetic and dermatologic care to improve skin texture, elasticity, and moisture retention.

• Adults, Elderly, and Pediatrics (if recommended by healthcare provider):
• Apply topically to affected skin areas once or twice daily.
• Use an amount sufficient to cover the affected region evenly, gently rubbing in.
• Use as needed to maintain skin hydration and comfort.
• Special Populations:
• Safe for sensitive skin and delicate areas under medical guidance.
• No dose adjustments required for renal or hepatic impairment due to topical use.
• Route:
• Topical application (cream, lotion, or emollient).
• Duration:
• Continuous use or as advised by a healthcare professional; may be used indefinitely for maintenance.

This formulation combines multiple agents with complementary effects. Urea acts as a keratolytic and humectant, softening the stratum corneum and attracting moisture. SyriCalm, a botanical extract complex, soothes irritated skin by modulating inflammation. Shea butter provides emollient and occlusive properties that nourish and protect the skin. The Oil Complex Omega Plus supplies essential omega fatty acids (ω-3, ω-6, ω-9) which support skin barrier integrity and reduce inflammation. Hydrolyzed silk proteins enhance skin smoothness and moisture retention by forming a protective film. Glycine Soja (Soybean) Oil offers antioxidant and conditioning benefits, promoting skin repair and elasticity. Together, these components restore hydration, reduce scaling, soothe irritation, and reinforce the skin barrier.

• Absorption: Minimal systemic absorption; primarily local action in skin layers.
• Distribution: Effects localized to epidermis and upper dermis.
• Metabolism: Components metabolized locally by skin enzymes; variable depending on botanical and lipid constituents.
• Excretion: Any absorbed traces cleared via normal metabolic pathways; negligible systemic presence.
• Onset of Action: Hydration and soothing effects generally apparent within hours to days; barrier restoration and keratolytic effects develop with continued use.

• Pregnancy: Considered safe for topical use during pregnancy due to minimal systemic absorption; use under medical advice.
• Lactation: Safe during breastfeeding; avoid nipple area to prevent infant ingestion.

• Dermatologic agent
• Emollient, humectant, keratolytic, and anti-inflammatory skin care formulation

• Hypersensitivity to any ingredient or excipients.
• Active skin infections or open wounds unless prescribed by a healthcare professional.

• Avoid contact with eyes and mucous membranes.
• Discontinue if allergic reactions such as rash, itching, or swelling occur.
• Use caution on severely damaged or broken skin.
• Not intended for treatment of active skin infections.

• Common: Mild local irritation, transient burning, redness, or itching.
• Rare: Allergic contact dermatitis or severe hypersensitivity (very rare).

• No significant drug-drug or drug-food interactions expected with topical use.
• May increase penetration of concomitant topical medications; monitor for enhanced effects or irritation.

• Increasing evidence supports the benefit of combined topical formulations with emollient and anti-inflammatory properties in managing chronic dry and inflammatory skin disorders.
• Recommended as adjunctive therapy in atopic dermatitis and xerosis treatment guidelines.
• No recent changes in safety profile or dosing guidelines reported.

• Store at 20°C to 25°C (68°F to 77°F).
• Protect from excessive heat, moisture, and direct sunlight.
• Keep container tightly closed when not in use.
• Keep out of reach of children.
• No refrigeration required.