TTO Thermal Toothpaste

Approved Indications:

• Relief of tooth hypersensitivity (due to exposed dentin or enamel erosion).
• Maintenance of daily oral hygiene.
• Reduction of oral bacteria and plaque.
• Supportive therapy in gingivitis and periodontitis.
• Protection of enamel and tooth remineralization.

Clinically Accepted Uses (Herbal / Antiseptic):

• Used as a natural antimicrobial and anti-inflammatory agent in oral conditions.
• Beneficial for sensitive teeth, inflamed gums, and oral mucosal irritation.
• Aids in mouth ulcer care and prevention of halitosis (bad breath).

Adults and Adolescents:

• Use a pea-sized amount of toothpaste.
• Brush teeth twice daily (morning and night) for at least 2 minutes.
• Spit out after brushing; do not swallow.

Children (above 6 years):

• Use under adult supervision to avoid swallowing.
• Same dosing as adults.

Special Groups:

• Geriatric: No dose adjustment needed.
• Pregnancy and Lactation: Use cautiously (see section 5).
• Renal/Hepatic Impairment: No adjustment required due to topical action.

TTO Thermal Toothpaste works through a combination of herbal and mineral ingredients:

• Potassium Nitrate (KNO₃): Desensitizes dental nerves by blocking transmission of pain stimuli.
• Tea Tree Oil (Melaleuca alternifolia): Broad-spectrum antimicrobial and anti-inflammatory activity.
• Propolis: Natural resin with antibacterial and healing properties for oral tissues.
• Sea Buckthorn Oil: Promotes mucosal healing and reduces inflammation.
• Echinacea Extract: Enhances local immunity and tissue repair.
• Geothermal Thermal Water: Rich in minerals that support enamel remineralization and oral freshness.

Together, these components help reduce sensitivity, support gum and tooth health, and maintain oral cleanliness.

• Absorption: Minimal systemic absorption; acts topically in the oral cavity.
• Distribution: Localized to teeth, gums, and mucosa.
• Metabolism: Herbal extracts are partially metabolized if swallowed in trace amounts.
• Excretion: Negligible systemic elimination.
• Onset of Action: Pain relief typically observed within a few days of regular use.

• Pregnancy: Considered safe for topical oral use. Ingredients like tea tree oil and propolis are not systemically absorbed in significant amounts.
• Lactation: Low risk; no harmful secretion into breast milk anticipated.
• Precaution: As with any topical oral product, it is advisable to consult a healthcare provider before use during pregnancy or breastfeeding.

• Pharmacologic Class: Herbal oral desensitizing agent
• Therapeutic Class: Topical dental product (non-fluoride)
• ATC Code: None officially assigned (herbal OTC)

• Known allergy or hypersensitivity to:
• Tea Tree Oil
• Propolis
• Echinacea
• Sea Buckthorn
• Potassium nitrate
• Children under 6 years unless supervised.
• Patients with a history of asthma or allergies to bee products or pollens (due to propolis/echinacea).

• Do not swallow.
• Avoid eye contact; rinse with water if accidental exposure occurs.
• If irritation, burning, or rash develops, discontinue use.
• Not a substitute for fluoride in populations at risk of caries unless combined with fluoride products.
• Keep out of reach of children.

Common (usually mild and temporary):

• Oral mucosal irritation
• Unusual or herbal taste

Less Common:

• Allergic reaction (e.g., gum swelling, rash, itching)
• Mild burning sensation if applied to damaged mucosa

Rare:

• Contact dermatitis
• Anaphylaxis (extremely rare; associated with propolis or echinacea sensitivity)

• No known significant drug interactions.
• Can be used safely alongside:
• Fluoride toothpastes (with proper rinsing)
• Chlorhexidine mouthwashes (administer separately)
• No interaction with food or beverages.

• Overdose Risk (Topical Use): Negligible.
• Ingestion of Large Amounts:
• May cause gastrointestinal upset (nausea, vomiting).
• Treat symptomatically; encourage fluid intake.
• Seek medical attention if large quantities are swallowed, especially by children.

• Store below 30°C in a cool, dry place.
• Do not freeze.
• Keep the cap tightly closed after use.
• Protect from direct sunlight and moisture.
• Shelf Life: Check printed expiration date on tube or carton.